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What Is THCV?

What is THCV - GLAKratom

While THC is an agonist of the CB1 receptor, THCV acts as an in inverse agonist, meaning it binds to the same receptor but produces an opposite pharmacological effect. Unlike THC, it might suppress the munchies.

In one study, THC users were given an oral dose of THCV shortly before being given a dose of THC, with the result being that none of them particularly felt the effects of the THC. However, because THCV occurs in such low concentrations in most cultivars, it’s pretty hard to ingest enough of it to counteract the effects of THC in the real world.


Although THCV looks molecularly identical to THC, it acts completely differently in the body and is not a scheduled controlled substance in the United States. THCV is federally legal as long as it’s extracted from hemp plants that contain less than 0.3% THC. At a state level, THCV is also permitted in all cannabis strains where medical and/or adult use is legal.

The Benefits Of THCV

Because it may suppress the appetite, THCV is currently being studied as a possible treatment for obesity. Research has shown that it might help to decrease food intake and trigger weight loss.


Like THC, CBD, and other cannabinoids, THCV exerts it’s possible relaxing effects through interaction with chemical receptors in nearly every system of the body. The two primary chemical receptors are called CB1 and CB2, which make up what is known as the Endocannabinoid System (ECS).

CB1 receptors are found throughout the body but are concentrated in the brain and nervous system, while CB2 receptors are more prevalent in the immune system. At low doses, THCV acts as an antagonist to CB1 receptors, which means it can block some of the actions caused by THC such as the munchies.

At higher doses, however, THCV activates both the CB1 and CB2 receptors, and exhibits effects that more closely resemble THC.

Where To Find THCV

As previously mentioned, THCV tends not to occur in high concentrations in hemp, although this impressive cannabinoid has generated quite an interest in high-THCV cultivars. As a result, it’s becoming slightly easier to come across strains that have been specifically bred to express this fascinating cannabinoid.

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